Harnessing the power of biology and data science to bring affordable and
sustainable biomanufactured products to market.

Lean Bioengineering:
Increased success, faster timelines, and lower costs

Our Lean Bioengineering approach combines the power of Directed Evolution, CRISPR+, and Machine Learning to make biomanufacturing scalable, cost-effective, and safe.

Engineering biology is slow, laborious, and expensive — until now

GenoScaler: A differentiated technology platform
Engineering biology is slow, laborious, and expensive — until now.

GenoScaler identifies and recombines edits to create strains with the highest commercial potential. The resulting data sets power machine learning models that efficiently search through large sequence spaces to rapidly improve performance.

Critical Steps to Strain Improvement

Critical Steps to Strain Improvement

Testing large sets of genetic solutions for improved traits

Discovery of beneficial genetic changes that impact improvement

Combinatorial testing of beneficial genetic changes

Traditional Strain Engineering

Traditional Strain Engineering

Tests 1 – 10 integrated genomic edits at a time

Discovers few (1−2) beneficial edits at a time

Limited to adding 1 beneficial edit at a time

Strain Engineering with GenoScaler™

Strain Engineering with GenoScaler™

2 – 4 weeks/​cycle is 4x faster than state-of-the-art

1,000x more cost effective at $0.10/variant

5 – 10x more efficient requiring only 0.5−3 FTE/​project

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